Structure of PDB 8ji8 Chain A Binding Site BS01

Receptor Information
>8ji8 Chain A (length=658) Species: 7159 (Aedes aegypti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNYKKNLLLLYDRPREPIFMGKGKSVFDVPDNYLTDRYRPIGPEIQNRFG
ELAEERIPVRSIALPDLRIPMSLGRQEQFSLFIPRHRKIAARLIDIFMGM
RNIEELQSCAVFARDRINPYLFNYALSVALLHRRDTKNLDLPSVVEVFPD
KYVDSRVFEQIREEATVVPEGMRMPIVIPKDFTASDLDEEHRLWYFREDI
GVNLHHWHWHLVYPGDGPDSVVRKDRRGELFYYMHSQLIARYNFERFCNR
LQRVKRLNNLREPIAEGYFPKLDSLVASRTWPGRVDNAVIKDLNRELDQI
KQDVSDLERWIDRIYEAVHQGYVVDESGNRIFLDEEKGIDILGNIIESSI
LSPNRQLYGDMHNVGHVFLSYTHDPDHRHLESFGVMGDVATAMRDPVFYR
WHSFIDDIFQEHKIKLPAYTKSQLTYEGISVTGIIVQSEGAPVNTLHTYW
QQSDVDLSRGMDFVPRGNVFARFTHLQHAPFQYVIQIDNTSDAQRMGFVR
IFMAPKNDERGQPMLFRDQRLFMVEMDKFLVALRPGANRIRRRSNESTVT
IPFERTFRFCGCGWPAHMLVPKGLPEGFPADLFVMVSNYEDDRVVQDLVD
AASYCGVRDRLYPDRKAMGFPFDRLARTGVDRLSNFVTPNMAIQSVNVIH
IDKTVPRT
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8ji8 Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ji8 Mosquitoes have evolved two types of prophenoloxidases
Resolution2.65 Å
Binding residue
(original residue number in PDB)		H362 H366 H402
Binding residue
(residue number reindexed from 1)		H362 H366 H402
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006582 melanin metabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ji8, PDBe:8ji8, PDBj:8ji8
PDBsum8ji8
PubMed
UniProtQ16G28

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