Structure of PDB 8jho Chain A Binding Site BS01

Receptor Information
>8jho Chain A (length=102) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDL
RFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRG
ER
Ligand information
>8jho Chain I (length=340) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
attcgatatcgagaatcccggtgccgaggccgctcaattggtcgtagaca
gctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgttttaacc
gccaaggggattactccctagtctccaggcacgtgtcagatatatacatc
ctgtgcatgtattgaaagtactgccagttctagactggagaatcccggtg
ccgaggccgctcaattggtcgtagacagctctagcaccgcttaaacgcac
gtacgcgctgtcccccgcgttttaaccgccaaggggattactccctagtc
tccaggcacgtgtcagatatatacatcctgtgcatgtatt
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8jho Structure of histone deacetylase complex Rpd3S bound to nucleosome
Resolution7.6 Å
Binding residue
(original residue number in PDB)		H39 R40 Y41 G44 V46 A47 R53 R63 K64 L65 R69 R83
Binding residue
(residue number reindexed from 1)		H7 R8 Y9 G12 V14 A15 R21 R31 K32 L33 R37 R51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8jho, PDBe:8jho, PDBj:8jho
PDBsum8jho
PubMed37798513
UniProtP84233|H32_XENLA Histone H3.2

[Back to BioLiP]