Structure of PDB 8jh4 Chain A Binding Site BS01

Receptor Information
>8jh4 Chain A (length=1400) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREG
GLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKK
VCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCCGN
TQPVVRKDGMKLWGTWKKSAQPERKLLTPGEILNVFKHISPEDCFRLGFN
EDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLTHKLSDILKANIN
VQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQALQKSGRPVKAI
RARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQVGVPISIAKTLS
YPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRIDLRYHKRAGDIV
LQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVMPYSTFRLNLSVT
SPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPVMGIVQ
DTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQPAILKPKPLWTGK
QLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVMFGVVDKKTVGSG
GGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFSIGIGDAIADAST
MKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRESFEGEVSRTLNDA
RDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSACVGQQMVEGKRI
AFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEFFFHAMAGREGLI
DTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDIIQFLYGEDGLDG
TQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVIEYAADILGDVEL
QKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRRIIQNAQQIFHLD
RAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQNATSLFQCLVRA
RLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGEMVGVIAAQSIGE
PATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIALDIEKAKVIQSS
IEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFSQSPWLLRLELDR
ARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLIIRCRVIEEDQML
KRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEYKNEELWALETDG
INLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSLYKEILNVIAFDG
SYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALMRCSFEETVEILF
EAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEKLLTSLPADYAPT
Ligand information
>8jh4 Chain N (length=166) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctttgtgtttggtgtgtttgggtggtggccgttttcgttgtttttttctg
tctcgtgcctggaatccccttggcggttaaaacgcgggggacagcgcgta
cgtgcgtttaagcggtgctagagctgtctacgaccaattgagcggcctcg
gcaccgggattctgat
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jh4 Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K100 H1390
Binding residue
(residue number reindexed from 1)		K99 H1327
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005665 RNA polymerase II, core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jh4, PDBe:8jh4, PDBj:8jh4
PDBsum8jh4
PubMed37981206
UniProtC4R4Y0

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