Structure of PDB 8j9g Chain A Binding Site BS01

Receptor Information
>8j9g Chain A (length=448) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPAQFHDQ
LKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTA
AYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGD
GTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFI
HARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGN
AYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDI
LALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKYYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8j9g Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		H207 R225 E226 T228 R243 F245 H251 L252 Y321 K395 L423 L433 P438 N439 N468 A469 G475 R481
Binding residue
(residue number reindexed from 1)		H148 R166 E167 T169 R184 F186 H192 L193 Y262 K336 L364 L374 P379 N380 N409 A410 G416 R422
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8j9g, PDBe:8j9g, PDBj:8j9g
PDBsum8j9g
PubMed37932527
UniProtA0A1I7NFD7

[Back to BioLiP]