Structure of PDB 8j8h Chain A Binding Site BS01

Receptor Information
>8j8h Chain A (length=452) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGSMKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQ
KGLQIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEIT
DEEIRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEI
FHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWT
ISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFL
DNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPK
EVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPI
MRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQV
LKDILALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKY
YI
Ligand information
>8j8h Chain E (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugacggcucuaaucuauuag
....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8j8h Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		H207 Q222 I223 L224 R225 T228 R243 F245 H251 T255 P323 E324 L423 S434 E436 N468 D474 G475 R481 I507
Binding residue
(residue number reindexed from 1)		H152 Q167 I168 L169 R170 T173 R188 F190 H196 T200 P268 E269 L368 S379 E381 N413 D419 G420 R426 I452
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8j8h, PDBe:8j8h, PDBj:8j8h
PDBsum8j8h
PubMed37932527
UniProtA0A1I7NFD7

[Back to BioLiP]