Structure of PDB 8j5s Chain A Binding Site BS01

Receptor Information
>8j5s Chain A (length=527) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADRRAAVGTTSDINQQDPATLQDGGNLRLSLTDFPPNFNILHIDGNNAEV
AAMMKATLPRAFIIGPDGSTTVDTNYFTSIELTRTAPQVVTYTINPEAVW
SDGTPITWRDIASQIHAISGADKAFEIASSSGAERVASVTRGVDDRQAVV
TFAKPYAEWRGMFAGNGMLLPASMTATPEAFNKGQLDGPGPSAGPFVVSA
LDRTAQRIVLTRNPRWWGARPRLDSITYLVLDDAARLPALQNNTIDATGV
GTLDQLTIAARTKGISIRRAPGPSWYHFTLNGAPGSILADKALRLAIAKG
IDRYTIARVAQYGLTSDPVPLNNHVFVAGQDGYQDNSGVVAYNPEQAKRE
LDALGWRRSGAFREKDGRQLVIRDLFYDAQSTRQFAQIAQHTLAQIGVKL
ELQAKSGSGFFSDYVNVGAFDIAQFGWVGDAFPLSSLTQIYASDGESNFG
KIGSPQIDAAIERTLAELDPGKARALANQVDELIWAEGFSLPLTQSPGTV
AVRSTLANFGATGLADLDYTAIGFMRR
Ligand information
>8j5s Chain E (length=8) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8j5s An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality
Resolution3.0 Å
Binding residue
(original residue number in PDB)
N111 A112 N230 Y340 F475 G490 W491 V492 S499 Q503
Binding residue
(residue number reindexed from 1)
N47 A48 N166 Y276 F411 G426 W427 V428 S435 Q439
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042277 peptide binding
GO:0043295 glutathione binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015833 peptide transport
GO:0017038 protein import
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8j5s, PDBe:8j5s, PDBj:8j5s
PDBsum8j5s
PubMed38548954
UniProtP9WGU5|Y1280_MYCTU Uncharacterized protein Rv1280c (Gene Name=Rv1280c)

[Back to BioLiP]