Structure of PDB 8j3s Chain A Binding Site BS01

Receptor Information
>8j3s Chain A (length=220) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAVALPLNINHDDTAVVG
HVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRTPFKHVALCSVGRRRGTLAVYGRDPEWVTQRFP
DLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERL
PKLRYDKQLVGVTEESYVKA
Ligand information
Receptor-Ligand Complex Structure
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PDB8j3s Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases
Resolution3.09 Å
Binding residue
(original residue number in PDB)		N62 H63 S132 L133 S134 S135 K156 C161 G164 R165 D227 I231 K237
Binding residue
(residue number reindexed from 1)		N42 H43 S112 L113 S114 S115 K121 C126 G129 R130 D192 I196 K202
Enzymatic activity
Enzyme Commision number 3.4.21.97: assemblin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8j3s, PDBe:8j3s, PDBj:8j3s
PDBsum8j3s
PubMed37974946
UniProtP16753|SCAF_HCMVA Capsid scaffolding protein (Gene Name=UL80)

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