Structure of PDB 8j3r Chain A Binding Site BS01

Receptor Information
>8j3r Chain A (length=422) Species: 1765684 (Sulfoacidibacillus thermotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIKVYRYEIVKPLDLDWKEFGTILRQLQQETRFALNKATQLAWEWMGFSS
DYKDNHGEYPKSKDILGYTNVHGYAYHTIKTKAYRLNSGNLSQTIKRATD
RFKAYQKEILRGDMSIPSYKRDHPLDLIKENISVNRMNHGDYIASLSLLS
NPAKQEMNVKRKISVIIIVRGAGKTIMDRILSGEYQVSASQIIHKDRKNK
WYLNISYRFEPQTRVLDLNKIMGIDLGVAVAAYMAFQHTPARYKLEGGEI
ENFRRQVESRRISMLRQGKYAGGARGGHGRDKRIKPIEQLRDKIANFRDT
TNHRYSRYIVDMAIKEGCGTIQMEDLTNIRDIGSRFLQNWTYYDLQQKII
YKAEEAGIKVIKIDPQYTSQRCSECGNIDSGNRIGQAIFKCRACGYEANA
DYNAARNIAIPNIDKIIAESIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8j3r Minimal and most efficient genome editing Cas enzyme
Resolution2.95 Å
Binding residue
(original residue number in PDB)
I2 Q93 K96 Y105 S188 A189 R291 R298 N339 T341 Y342 Y343
Binding residue
(residue number reindexed from 1)
I2 Q93 K96 Y105 S188 A189 R291 R298 N339 T341 Y342 Y343
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8j3r, PDBe:8j3r, PDBj:8j3r
PDBsum8j3r
PubMed
UniProtA0A2U3D0N8|CS12F_SULT2 CRISPR-associated endodeoxyribonuclease Cas12f1 (Gene Name=cas12f1)

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