Structure of PDB 8iya Chain A Binding Site BS01
Receptor Information
>8iya Chain A (length=161) Species:
9606
(Homo sapiens) [
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LEVLFQGPNSKLLSTSAKRIQKELADITLDPPPNSSAGPKGDNIYEWRST
ILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHPNINSQGVICL
DILKDNWSPALTISKVLLSISSLLTDPNPADPLVGSIATQYMTNRAEHDR
MARQWTKRYAT
Ligand information
>8iya Chain E (length=6) Species:
9606
(Homo sapiens) [
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CEGYES
Receptor-Ligand Complex Structure
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PDB
8iya
Complex of SETDB1-derived peptide bound to UBE2E1
Resolution
2.43 Å
Binding residue
(original residue number in PDB)
N125 S126 C131 K136 L165 V166 G167 S168
Binding residue
(residue number reindexed from 1)
N93 S94 C99 K104 L133 V134 G135 S136
Enzymatic activity
Enzyme Commision number
2.3.2.23
: E2 ubiquitin-conjugating enzyme.
2.3.2.24
: (E3-independent) E2 ubiquitin-conjugating enzyme.
External links
PDB
RCSB:8iya
,
PDBe:8iya
,
PDBj:8iya
PDBsum
8iya
PubMed
38341401
UniProt
P51965
|UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E1 (Gene Name=UBE2E1)
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