Structure of PDB 8isz Chain A Binding Site BS01

Receptor Information
>8isz Chain A (length=465) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKY
CRPNSVLYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPI
RDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSK
NPQNACCAAQMFLDNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQA
LESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSK
PLKLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIF
IEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTLRFANKIGEILTA
STEIKTPPLAFKYYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8isz Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
Resolution3.27 Å
Binding residue
(original residue number in PDB)		E289 Y328 R362 R364 S391
Binding residue
(residue number reindexed from 1)		E247 Y286 R320 R322 S349
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8isz, PDBe:8isz, PDBj:8isz
PDBsum8isz
PubMed37783228
UniProtA0A1I7NFD7

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