Structure of PDB 8ir2 Chain A Binding Site BS01

Receptor Information
>8ir2 Chain A (length=196) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKHIIQMTGFKMEEKEALVKLLLKLDCTFIKSEKYKNCTHLIAERLCKSE
KFLAACAAGKWILTKDYIIHSAKSGRWLDETTYEWGYKIEKDSRYSPQMQ
SAPKRWREELKRTGAPGAFHRWKVVLLVRTDKRSDSLIRVLEAGKANVIL
PKSSPSGITHVIASNARIKAEKEKDNFKAPFYPIQYLGDFLLEKLE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ir2 Structural insights into Rad18 targeting by the SLF1 BRCT domains.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		T13 M17 K20 K36 E38 R50 K53 S54 K56 R134 Q190
Binding residue
(residue number reindexed from 1)		T8 M12 K15 K31 E33 R45 K48 S49 K51 R129 Q185
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:2000781 positive regulation of double-strand break repair

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Biological Process
External links
PDB RCSB:8ir2, PDBe:8ir2, PDBj:8ir2
PDBsum8ir2
PubMed37748650
UniProtQ9BQI6|SLF1_HUMAN SMC5-SMC6 complex localization factor protein 1 (Gene Name=SLF1)

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