Structure of PDB 8im5 Chain A Binding Site BS01

Receptor Information
>8im5 Chain A (length=66) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSPEPVGWQCPGCTFINKPTRPGCEMCCRARPETYQIPASYQPDEEE
RARLAGEEEALRQYQQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8im5 Chain A Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8im5 Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity.
ResolutionN/A
Binding residue
(original residue number in PDB)
C13 C27 C30
Binding residue
(residue number reindexed from 1)
C13 C27 C30
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
External links
PDB RCSB:8im5, PDBe:8im5, PDBj:8im5
PDBsum8im5
PubMed37595872
UniProtQ9WUB0|HOIL1_MOUSE RanBP-type and C3HC4-type zinc finger-containing protein 1 (Gene Name=Rbck1)

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