Structure of PDB 8ikx Chain A Binding Site BS01

Receptor Information
>8ikx Chain A (length=390) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTINVLDHGAKGDGTSDDTKAFEDAWQVACKVAASTLLVPSGSTFLVGPV
SFLGKECKEKIVFQLEGKIIAPTSASAWGSGLLQWIEFKALQGITIKGKG
IIDGRGSVWWNDMMGTKMPRTKPTALRFYGSNGVTVSGITIQNSPQTHLK
FDNCISIQVSDFTTSSPGDSPNTDGIHLQNSQDAVIYRSTLACGDDCISI
QTGCSNINIHDVDCGPGHGISIGGLGKDNTKACVSNITVRDVTMHETTNG
VRIKSWQGGSGSVKQVMFSNIQVSNVANPIIIDQYYCDGGGCHNETSAVA
VSNINYINIKGTYTKEPVRFACSDSLPCTGISLSTIELKPATGKASSLDP
FCWKAHGELKTKTLPPIQCLKTEKSPEAASRSNNDACHHH
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain8ikx Chain B Residue 5 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ikx A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		F399 C400 C417
Binding residue
(residue number reindexed from 1)		F351 C352 C369
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004650 polygalacturonase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016829 lyase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009827 plant-type cell wall modification
Cellular Component
GO:0009505 plant-type cell wall

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ikx, PDBe:8ikx, PDBj:8ikx
PDBsum8ikx
PubMed38359129
UniProtQ9LYJ5

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