Structure of PDB 8iht Chain A Binding Site BS01

Receptor Information
>8iht Chain A (length=121) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARTKQTARKSTGGKAPRKQLATKAPHRYRPGTVALREIRRYQKSTELLIR
KLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLAAIH
AKRVTIMPKDIQLARRIRGER
Ligand information
>8iht Chain I (length=158) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttactggccgccctggagaatcccggtgccgaggccgctcaattggtcgt
agacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgttt
taaccgccaaggggattactccctagtctccaggcacgtgtcagatatat
acatcctg
Receptor-Ligand Complex Structure
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PDB8iht Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Resolution3.72 Å
Binding residue
(original residue number in PDB)		Y41 R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117
Binding residue
(residue number reindexed from 1)		Y28 R29 T32 R50 R59 R70 F71 Q72 S73 R103 V104
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8iht, PDBe:8iht, PDBj:8iht
PDBsum8iht
PubMed37845487
UniProtP84233|H32_XENLA Histone H3.2

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