Structure of PDB 8igt Chain A Binding Site BS01

Receptor Information
>8igt Chain A (length=208) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFLHAVDVVLDPDTAHPDLFLSEDRRSVRRCPFRHLGESVPDNPERFDSQ
PCVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEVLLIPQNGFW
TLEMHKGQYRAVSSPDRILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHI
YTCPRSAFSVPVRPFFRLGCEDSPIFICPALTGANGVTVPEEGLTLHRVS
LLEHHHHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8igt Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8igt Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Resolution1.56 Å
Binding residue
(original residue number in PDB)		C353 H357 H530 H532
Binding residue
(residue number reindexed from 1)		C31 H35 H204 H206
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8igt, PDBe:8igt, PDBj:8igt
PDBsum8igt
PubMed37674084
UniProtQ7KYR7|BT2A1_HUMAN Butyrophilin subfamily 2 member A1 (Gene Name=BTN2A1)

[Back to BioLiP]