Structure of PDB 8ide Chain A Binding Site BS01

Receptor Information
>8ide Chain A (length=929) Species: 1349410 (Pandoravirus salinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATGANFERRVTILGIESSCDDTGVAVLQVGGNAPPAVLAHEAVTSAAVHR
ETVAPLVDQAMAASGVGWDAIDAIAVTVGPGMMGGLMAGVDEAVRLAALH
GKPLVPVNHLEGHALVAGVCTRQLCFPFLVLLASGGSCQLVLARDLGDYR
RLGQTLDCAPGQALDAVARALALDLGASGSGGRAIELAAKNARTDAGDDR
IGDDAWPDGCDFAFGGLRDRAVALARKSLAGEADDIAKRVQALIVDQLVS
RTVRAIEWCRAHVADPTALVVAGGVAANTCLRESLQRAIGSVDLVCPPPR
LCTDNGVMIAHAGALHYLHRPDAFACGPTHVCLQHEWHLGVDVSECVRAD
RPVPQVAAIHASIKSDVADAARALCRGELVAFPTETVYGLGADAASDEAV
QRIFDAKGRPSNNPIIVHVASKEQFYRIAGHDLDAALRARCERLMDEFWP
GPLTLLVPNGGEKLSPLVTCGLPVVGLRMPDNATAIDLIRRAGVGVAAPS
ANKSGRPSPTCAQHVAADLVGERIWGVLDGRGSTYGIESTVLDVATVSIY
REGPVTADDISRALDGAPVDRHYAPDTDVTVVHGTLGFLNATVRSMRDRG
LRVGVIAPYGDAIDARASKVWYCMRHGDGSLGANLYAALRGLDLPDVDVI
LVRAVPDSRTGGAVMERLAKASQGSRLIEPAMTARLERMIGADVVQRIAR
GRVLVCGLGGAGAPLVDMAVRAGVGRLGLLDPDRVDLSNLVRMPQATLAD
VDRRKIDVVAERARAVNPDADLTLLAHRITPDFDMGALRAHEYDIIVDAV
DDPAGKVALIKYAVENKLPLISCMGAGNKTDVTQVHRVVDIADADVCLLA
LETKRLLAKEGITRGVKCVVTQGDHWVFAIGNWPPCYFMAAAVLLDHVLR
VLAGPESVEDHVRGRAVGVSTKSGIVAIP
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8ide Chain A Residue 1101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ide Structure-function analysis of an ancient TsaD-TsaC-SUA5-TcdA modular enzyme reveals a prototype of tRNA t6A and ct6A synthetases.
Resolution3.21 Å
Binding residue
(original residue number in PDB)
H155 H159 D350
Binding residue
(residue number reindexed from 1)
H109 H113 D304
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding
GO:0008641 ubiquitin-like modifier activating enzyme activity
GO:0016746 acyltransferase activity
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0008033 tRNA processing

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Molecular Function

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Biological Process
External links
PDB RCSB:8ide, PDBe:8ide, PDBj:8ide
PDBsum8ide
PubMed37427786
UniProtA0A291ATS8

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