Structure of PDB 8i89 Chain A Binding Site BS01

Receptor Information
>8i89 Chain A (length=280) Species: 2001 (Streptosporangium roseum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGILQANRVLLSRLLPGVEPEGLTVRHGQFHQVVIASDRVVCLPRTAAAA
ARLPRRAAVMRVLAGLDLGCRTPRPLCEGSLPFLVLSRVPGAPLEADALE
DSKVAEVVAAQYVTLLSGLASAGADEKVRAALPAPQGRWRQFAADVRAEL
FPLMSDGGCRQAERELAALDSLPDITEAVVHGNLGAENVLWVRDDGLPRL
SGVIDWDEVSIGDPAEDLAAIGAGYGKDFLDQVLTLGGWSDRRMATRIAT
IRATFALQQALSACRDGDEEELADGLTGYR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i89 Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		W145 G188 N189 G191 E193 E222 A226 A229 F261 Q264 Q265 E277
Binding residue
(residue number reindexed from 1)		W139 G182 N183 G185 E187 E216 A220 A223 F255 Q258 Q259 E271
Enzymatic activity
Enzyme Commision number 2.7.1.103: viomycin kinase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0050394 viomycin kinase activity
Biological Process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8i89, PDBe:8i89, PDBj:8i89
PDBsum8i89
PubMed38114770
UniProtD2B3F1

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