Structure of PDB 8i84 Chain A Binding Site BS01

Receptor Information
>8i84 Chain A (length=278) Species: 2001 (Streptosporangium roseum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGILQANRVLLSRLLPGVEPEGLTVRHGQFHQVVIASDRVVCLPRTAAAA
ARLPRRAAVMRVLAGLDLGCRTPRPLCEGPFLVLSRVPGAPLEADALEDS
KVAEVVAAQYVTLLSGLASAGADEKVRAALPAPQGRWRQFAADVRAELFP
LMSDGGCRQAERELAALDSLPDITEAVVHGNLGAENVLWVRDDGLPRLSG
VIDWDEVSIGDPAEDLAAIGAGYGKDFLDQVLTLGGWSDRRMATRIATIR
ATFALQQALSACRDGDEEELADGLTGYR
Ligand information
>8i84 Chain D (length=6) Species: 66854 (Saccharothrix mutabilis subsp. capreolus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KAARAA
Receptor-Ligand Complex Structure
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PDB8i84 Discovery and characterization of genes conferring natural resistance to the antituberculosis antibiotic capreomycin.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		G188 N189 E193 E214 F261 A262 Q264 Q265 S268 D272 E277
Binding residue
(residue number reindexed from 1)		G180 N181 E185 E206 F253 A254 Q256 Q257 S260 D264 E269
Enzymatic activity
Enzyme Commision number 2.7.1.103: viomycin kinase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016301 kinase activity
GO:0050394 viomycin kinase activity
Biological Process
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8i84, PDBe:8i84, PDBj:8i84
PDBsum8i84
PubMed38114770
UniProtD2B3F1

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