Structure of PDB 8hzy Chain A Binding Site BS01

Receptor Information
>8hzy Chain A (length=462) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APAERCAHPGADLGAAVHAVGQTLAAGGLVPPDEAGTTARHLVRLAVRYG
NSPFTPLEEARHDLGVDRDAFRRLLALFGQVPELRTAVETGPAGAYWKNT
LLPLEQRGVFDAALARKPVFPYSVGLYPGPTCMFRCHFCVRVTGARYDPS
ALDAGNAMFRSVIDEIPAGNPSAMYFSGGLEPLTNPGLGSLAAHATDHGL
RPTVYTNSFALTERTLERQPGLWGLHAIRTSLYGLNDEEYEQTTGKKAAF
RRVRENLRRFQQLRAERESPINLGFAYIVLPGRASRLLDLVDFIADLNDA
GQGRTIDFVNIREDAELQEALNAFEERVRERTPGLHIDYGYALNSLRTGA
DAELLRIKPATMRPTAHPQVAVQVDLLGDVYLYREAGFPDLDGATRYIAG
RVTPDTSLTEVVRDFVERGGEVAAVDGDEYFMDGFDQVVTARLNQLERDA
ADGWEEARGFLR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8hzy Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hzy Mechanistic Insights from the Crystal Structure and Computational Analysis of the Radical SAM Deaminase DesII.
Resolution2.03979 Å
Binding residue
(original residue number in PDB)		C141 F143 C145 C148 R150 L189 Y242
Binding residue
(residue number reindexed from 1)		C132 F134 C136 C139 R141 L180 Y233
Annotation score1
External links
PDB RCSB:8hzy, PDBe:8hzy, PDBj:8hzy
PDBsum8hzy
PubMed38943270
UniProtQ9ZGH1|DESII_STRVZ dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase (Gene Name=desII)

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