Structure of PDB 8hwa Chain A Binding Site BS01

Receptor Information
>8hwa Chain A (length=700) Species: 10244 (Monkeypox virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDAAIRGNDVIFVLKTIGVPSACRQNEDPRFVEAFKCDELERYIDNNPEC
TLFESLRDEEAYSIVRIFMDVDLDACLDEIDYLTAIQDFIIEVSNCVARF
AFTECGAIHENVIKSMRSNFSLTKSTNRDKTSFHIIFLDTYTTMDTLIAM
KRTLLELSRSSENPLTRSIDTAVYRRKTTLRVVGTRKNPNCDTIHVMQPP
HDNIEDYLFTYVDMNNNSYYFSLQRRLEDLVPDKLWEPGFISFEDAIKRV
SKIFINSIINFNDLDENNFTTVPLVIDYVTPCALCKKRSHKHPHQLSLEN
GAIRIYKTGNPHSCKVKIVPLDGNKLFNIAQRILDTNSVLLTERGDHIVW
INNSWKFNSEEPLITKLILSIRHQLPKEYSSELLCPRKRKTVEANIRDML
VDSVETDTYPDKLPFKNGVLDLVDGMFYSGDDAKKYTCTVSTGFKFDDTK
FVEDSPEMEELMNIINDIQPLTDENKKNRELYEKTLSSCLCGATKGCLTF
FFGETATGKSTTKRLLKSAIGDLFVETGQTILTDVLDKGPNPFIANMHLK
RSVFCSELPDFACSGSKKIRSDNIKKLTEPCVIGRPCFSNKINNRNHATI
IIDTNYKPVFDRIDNALMRRIAVVRFRTHFSQPSGREAAENNDAYDKVKL
LDEGLDGKIQNNRYRFAFLYLLVKWYKKYHIPIMKLYPTPEEIPDFAFYL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8hwa Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		R585 F588
Binding residue
(residue number reindexed from 1)		R585 F588
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0030430 host cell cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:8hwa, PDBe:8hwa, PDBj:8hwa
PDBsum8hwa
PubMed38177671
UniProtA0A7H0DN89|PG117_MONPV Uncoating factor OPG117 (Gene Name=OPG117)

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