Structure of PDB 8hsr Chain A Binding Site BS01

Receptor Information

>8hsr Chain A (length=361) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RLVKGYLEISQDGYGFLTENLHNLESRVAIVSAGLIKQYALRAGDYVVGQ
ARPPRENERYATLLKVEAVNNLDPEAAKNRPRFDELTPQFPDRQIRLETT
PDELSTRVIDLLAPIGRGQRGLIVAPPKAGKTTLLKKIANAVLKNEPDIK
VIVLLIDERPEEVTDFRESVQGAEVIASTFDEPPQNHIRVAEFVHERAKR
IVEEGGHVMILLDSITRLARANNLVTPPTGRTLSGGLDSAALYFPKRFLG
AARNIRGGGSLTILATALVETGSRMDDVIFEEFKGTGNMELHLSRRLEER
RIFPAIDILKSGTRREELLLGEEVTHKMWLLRKVLADMDPAEAMEMLLAR
LARTKNNKEFL

Ligand information

>8hsr Chain R (length=29) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

uacccauaaccauaucuccacauccaccu

.............................

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8hsr Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
Resolution	4.0 Å
Binding residue (original residue number in PDB)	R290 T291
Binding residue (residue number reindexed from 1)	R231 T232

Enzymatic activity

Enzyme Commision number

3.6.4.-

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0008186	ATP-dependent activity, acting on RNA
GO:0016787	hydrolase activity
GO:0016887	ATP hydrolysis activity

	Biological Process
GO:0006353	DNA-templated transcription termination

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Molecular Function

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Biological Process

External links

PDB	RCSB:8hsr, PDBe:8hsr, PDBj:8hsr
PDBsum	8hsr
PubMed	36753546
UniProt	Q5SJE9

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