Structure of PDB 8hbm Chain A Binding Site BS01

Receptor Information
>8hbm Chain A (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEER
Ligand information
Receptor-Ligand Complex Structure
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PDB8hbm Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA
Resolution3.3 Å
Binding residue
(original residue number in PDB)		K145 H146 Y147 K160 R164 Q206 R209
Binding residue
(residue number reindexed from 1)		K15 H16 Y17 K30 R34 Q76 R79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8hbm, PDBe:8hbm, PDBj:8hbm
PDBsum8hbm
PubMed37287811
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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