Structure of PDB 8h9d Chain A Binding Site BS01

Receptor Information
>8h9d Chain A (length=1114) Species: 1898203 (Lachnospiraceae bacterium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LMYYESLTKQYPVSKTIRNELIPIGKTLDNIRQNNILESDVKRKQNYEHV
KGILDEYHKQLINEALDNCTLPSLKIAAEIYLKNQKEVSDREDFNKTQDL
LRKEVVEKLKAHENFTKIGKKDILDLLEKLPSEDDYNALESFRNFYTYFT
SYNKVRENLYSDKEKSSTVAYRLINENFPKFLDNVKSYRFVKTAGILADG
LGEEEQDSLFIVETFNKTLTQDGIDTYNSQVGKINSSINLYNQKNFRKIP
KMKMLYKQILSDDEFQSDEVLIDNVESYGSVLIESLKSSKVSAFFDALRE
SKGKNVYVKNDKSYSLEHLCNLSCNLIENYIHQISDDIENIIINNETFLR
IVINEHDRSRKLAKNRKAVKAIKDFLDSIKVLERELKLINSSGQELEKDL
IVYSAHEELLVELKQVDSLYNMTRNYLTKKPFSTEKVKLNFNRSTLLNGW
DRNKETDNLGVLLLKDGKYYLGIMNTSANKAFVNPPVAKTEKVFKKVDYK
LLPVPNQMLPKVFFAKSNIDFYNPSSEIYSNYKKGTHKKGNMFSLEDCHN
LIDFFKESISKHEDWSKFGFKFSDTASYNDISEFYREVEKQGYKLTYTDI
DETYINDLIERNELYLFQIYNKDFSMYSKGKLNLHTLYFMMLFDQRNIDD
VVYKLNGEAEVFYRPASISEDELIIHKAGEEIKNKNPNRARTKETSTFSY
DIVKDKRYSKDKFTLHIPITMNFGVDEVKRFNDAVNSAIRIDENVNVIGI
DRGERNLLYVVVIDSKGNILEQISLNSIINKEYDIETDYHALLDEREKDW
NTVENIRDLKAGYLSQVVNVVAKLVLKYNAIICLEDLNFGGRQKVEKQVY
QKFEKMLIDKLNYLVIDKSREQTSPKELGGALNALQLTSKFKSFKELGKQ
SGVIYYVPAYLTSKIDPTTGFANLFYMSKRFFDGFDFIRFNALENVFEFG
FDYRSFTQRACGINSKWTVCTNGERIIKYEKVVVVTDEMKNLFEQYKIPY
EDGRNVKDMIISNEEAEFYRRLYRLLQQTLQMRNSTSDGTRDYIISPVKN
KREAYFNSELSDGSVPKDADANGAYNIARKGLWVLEQIRQKSEGEKINLA
MTNAEWLEYAQTHL
Ligand information
>8h9d Chain G (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauuucuacuaaguguagauc
....<<<<<.....>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8h9d Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R17 N18 E19 N685 K686 S689 Y691 S692 K693 G694 K695 N697 L698 H699 R728 H740 I746 K747 N748 K749 N750 R753 K757 S760 F762 Y764 V767 K768 D769 K770 R771 Y772 K776 N844 I849 Y853 L856 R860 G883 S886 Q887 N890 D933 K934 K942
Binding residue
(residue number reindexed from 1)		R18 N19 E20 N621 K622 S625 Y627 S628 K629 G630 K631 N633 L634 H635 R664 H676 I682 K683 N684 K685 N686 R689 K693 S696 F698 Y700 V703 K704 D705 K706 R707 Y708 K712 N780 I785 Y789 L792 R796 G812 S815 Q816 N819 D859 K860 K868
External links