Structure of PDB 8gu7 Chain A Binding Site BS01

Receptor Information
>8gu7 Chain A (length=37) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSEGKRLTDQLRWKIMSLKMRIEQLKQTISKLNEEMK
Ligand information
>8gu7 Chain D (length=28) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EAAALRAELRDLELEEARLVQELEDVDR
Receptor-Ligand Complex Structure
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PDB8gu7 The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
I17 L20 R23 I24 I31
Binding residue
(residue number reindexed from 1)
I15 L18 R21 I22 I29
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8gu7, PDBe:8gu7, PDBj:8gu7
PDBsum8gu7
PubMed37409929
UniProtQ8CDJ3|BAKOR_MOUSE Beclin 1-associated autophagy-related key regulator (Gene Name=Atg14)

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