Structure of PDB 8gj2 Chain A Binding Site BS01

Receptor Information
>8gj2 Chain A (length=343) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAAQGFEEH
HTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTL
TGLLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRW
VAARAKQLNLELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLP
RVEQAVNDAAHFTPFHWVDALLMGKSKRALHILQQLRLEGSEPVILLRTL
QRELLLLVNLKRQSAHTPLRALFDKHRVWQNRRGMMGEALNRLSQTQLRQ
AVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHKPLADVFIDG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8gj2 Structural characterisation of the complete cycle of sliding clamp loading in E. coli
Resolution2.6 Å
Binding residue
(original residue number in PDB)		F215 V244 I245 R248 R252 W279 K313
Binding residue
(residue number reindexed from 1)		F215 V244 I245 R248 R252 W279 K313
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0009360 DNA polymerase III complex
GO:0030894 replisome
GO:0043846 DNA polymerase III, clamp loader complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8gj2, PDBe:8gj2, PDBj:8gj2
PDBsum8gj2
PubMed
UniProtP28630|HOLA_ECOLI DNA polymerase III subunit delta (Gene Name=holA)

[Back to BioLiP]