Structure of PDB 8g6c Chain A Binding Site BS01

Receptor Information
>8g6c Chain A (length=248) Species: 28450 (Burkholderia pseudomallei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QMPIQRVGVRAVRHPLTVRTAEGETQATVGTWNLDVHLPADQKGTHMSRF
VALLEERGGPLTADAFRTMLATMLEKLEARAGRIEVSFPYFVNKTAPVSG
VRSLLDYEVTLTGDVRDGLTRVFAKVLVPVTSLCPCSKKISQYGAHNQRS
HVTIDAELAADVPVEDLIRIAEEEASCELWGLLKRPDEKFVTERAYENPK
FVEDLVRDVARRLDADERIVAYVLEAENFESIHNHSAYALIERDKRRG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8g6c Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8g6c Towards automated crystallographic structure refinement with phenix.refine.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		C154 H166
Binding residue
(residue number reindexed from 1)		C134 H146
Annotation score1
Enzymatic activity
Enzyme Commision number 3.5.4.16: GTP cyclohydrolase I.
Gene Ontology
Molecular Function
GO:0003933 GTP cyclohydrolase activity
GO:0003934 GTP cyclohydrolase I activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0046654 tetrahydrofolate biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8g6c, PDBe:8g6c, PDBj:8g6c
PDBsum8g6c
PubMed
UniProtA0A069BB45

[Back to BioLiP]