Structure of PDB 8g57 Chain A Binding Site BS01

Receptor Information
>8g57 Chain A (length=109) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKQTARKSTGKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIA
QDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQ
LARRIRGER
Ligand information
>8g57 Chain I (length=150) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgcacaggatgtatatatctgacacgtgcctggagactagggagtaatcc
ccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtg
ctagagctgtctacgaccaattgagcggcctcggcaccgggattctcgat
Receptor-Ligand Complex Structure
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PDB8g57 Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		Q5 R40 V46 R63 K64 L65 R69 R83
Binding residue
(residue number reindexed from 1)		Q3 R15 V21 R38 K39 L40 R44 R58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8g57, PDBe:8g57, PDBj:8g57
PDBsum8g57
PubMed37058572
UniProtP84233|H32_XENLA Histone H3.2

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