Structure of PDB 8g2p Chain A Binding Site BS01
Receptor Information
>8g2p Chain A (length=347) Species:
10090
(Mus musculus) [
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DKLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNT
GSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFGNPLSHFL
EGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPE
EISVNIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKQG
ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKK
EFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECL
RTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFDKL
Ligand information
>8g2p Chain E (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
8g2p
Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and GTP
Resolution
2.521 Å
Binding residue
(original residue number in PDB)
R158 L159 K160 R161 H203 E386 K395
Binding residue
(residue number reindexed from 1)
R11 L12 K13 R14 H56 E226 K235
External links
PDB
RCSB:8g2p
,
PDBe:8g2p
,
PDBj:8g2p
PDBsum
8g2p
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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