Structure of PDB 8fz4 Chain A Binding Site BS01

Receptor Information
>8fz4 Chain A (length=177) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SARRAFDLYFVLDKSGSVANNWIEIYNFVQQLAERFVSPEMRLSFIVFSS
QATIILPLTGDRGKISKGLEDLKRVSPVGETYIHEGLKLANEQIQKAGGL
KTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYAVGVLDFEQAQLE
RIADSKEQVFPVKGGFQALKGIINSIL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8fz4 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fz4 Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Resolution2.19 Å
Binding residue
(original residue number in PDB)		D50 S52 S54 T118 D148
Binding residue
(residue number reindexed from 1)		D13 S15 S17 T81 D111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8fz4, PDBe:8fz4, PDBj:8fz4
PDBsum8fz4
PubMed37747038
UniProtP58335|ANTR2_HUMAN Anthrax toxin receptor 2 (Gene Name=ANTXR2)

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