Structure of PDB 8fxu Chain A Binding Site BS01

Receptor Information
>8fxu Chain A (length=310) Species: 1517 (Thermoanaerobacterium thermosaccharolyticum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKQLNIGVAIYKFDDTCMTGVRNAMTAEAQGKAKLNMVDSQNSQPTQNDQ
VDLFITKKMNALAINPVDRTAAGTIIDKAKQANIPVVFFNREPLPEDMKK
WDKVYYVGAKAEQSGILQGQIMADYWKAHPEADKNHDGVMQYVMLMGQPG
HQDAILRTQYSIQTVKDAGIKVQELAKDYANWDRVTAHDKMAAWLSSFGD
KIEAVFANNDDMALGAIEALKSAGYFTGKYIPVVGVDATAPGIQAIKDGT
LLGTVLNDAKNQAKATFNIAYELAQGITPTKDNIGYDITDGKYVWIPYKK
ITKDNISDAE
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain8fxu Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fxu Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching.
Resolution1.59 Å
Binding residue
(original residue number in PDB)		D15 N90 R91 D153 R157 W182 N209 D238
Binding residue
(residue number reindexed from 1)		D15 N90 R91 D153 R157 W182 N209 D237
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:8fxu, PDBe:8fxu, PDBj:8fxu
PDBsum8fxu
PubMed37598249
UniProtD9TSJ1

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