Structure of PDB 8fxq Chain A Binding Site BS01

Receptor Information
>8fxq Chain A (length=324) Species: 4843 (Rhizopus microsporus var. chinensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVGTVPMTDYGNDIEYYGQVTIGTPGKKFNLDFDTGSSDLWIASTLCTNC
GSRQTKYDPNQSSTYQADGRTWSISYGDGSSASGILAKDNVNLGGLLIKG
QTIELAKREAASFANGPNDGLLGLGFDTITTVRGVKTPMDNLISQGLISR
PIFGVYLGKASNGGGGEYIFGGYDSTKFKGSLTTVPIDNSRGWWGITVDR
ATVGTSTVASSFDGILDTGTTLLILPNNVAASVARAYGASDNGDGTYTIS
CDTSRFKPLVFSINGASFQVSPDSLVFEEYQGQCIAGFGYGNFDFAIIGD
TFLKNNYVVFNQGVPEVQIAPVAE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fxq Aspartic protease inhibitors designed from computer-generated templates bind as predicted.
Resolution1.21 Å
Binding residue
(original residue number in PDB)		D35 Y77 G78 D79 F114 D218 G220 T221 T222
Binding residue
(residue number reindexed from 1)		D34 Y76 G77 D78 F113 D217 G219 T220 T221
Enzymatic activity
Enzyme Commision number 3.4.23.21: rhizopuspepsin.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8fxq, PDBe:8fxq, PDBj:8fxq
PDBsum8fxq
PubMed11463303
UniProtP06026|CARP_RHICH Rhizopuspepsin

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