Structure of PDB 8fti Chain A Binding Site BS01

Receptor Information
>8fti Chain A (length=737) Species: 2026780 (Planctomycetota bacterium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSIDEYQGARKWCFTIAFNKALVNRDKNDGLFVESLLRHEKYSKHDWYDE
DTRALIKCSTQAANAKAEALANYFSAYRHSPGCLTFTAEDELRTIMERAY
ERAIFECRRRETEVIIEFPSLFEGDRITTAGVVFFVSFFVERRVLDRLYG
AVSGLKKNEGQYKLTRKALSMYCLKDSRFTKAWDKRVLLFRDILAQLGRI
PAEAYEYYHGEQGDDNEGTNPKRHKDKFIEFALHYLEAQHSEICFGRRHI
VRKHRTKGKVVVDFSKKDEDQSYYISKNNVIVRIDKNAGPRSYRMGLNEL
KYLVLLSLQGKGDDAIAKLYRYRQHVENILDVVKVTDKDNHVFLPRFVLE
QHGIGRKAFKQRIDGRVKHVRGVWEKKKAATNEMTLHEKARDILQYVNEN
CTRSFNPGEYNRLLVCLVGKDVENFQAGLKRLQLAERIDGRVYSIFAQTS
TINEMHQVVCDQILNRLCRIGDQKLYDYVGLGKKDEIDYKQKVAWFKEHI
SIRRGFLRKKFWYDSKKGFAKLVEEHLESGGGQRDVGLDKKYYHIDAIGR
FEGANPALYETLARDRLCLMMAQYFLGSVRKELGNKIVWSNDSIELPVEG
SVGNEKSIVFSVSDYGKLYVLDDAEFLGRICEYFMPHEKGKIRYHTVYEK
GFRAYNDLQKKCVEAVLAFEEKVVKAKKDFREILAQTMCKEAEKTAVNKV
ARAFFAHHLKFVIDEFGLFSDVMKKYGIEKEWKFPVK
Ligand information
>8fti Chain B (length=97) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaagaagaguuuauucagauagauuuguccggacaaaucuaucugaaua
aacucuucuucgcuggagcagcccccgauuuguggggugauuacagc
.<<<<<<<<<<<<<<<<<<<<<<<<<<<<<..>>>>>>>>>>>>>>>>>>
>>>>>>>>>>><<<......<<<<<........>>>>>......>>>
Receptor-Ligand Complex Structure
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PDB8fti Structural basis for the activation of a compact CRISPR-Cas13 nuclease
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R155 D159 S190 R191 F192 T193 R204 D205 E235 K243 Y302 K305 R322 F371 P373 R374 F375 R394 W402 L414 H415 S432 P435 Y438 V446 Y506 V507 K511 K512 D513 K520 W523 S529 R531 R532 K537 R578 F579 P584 E588 H673 R681
Binding residue
(residue number reindexed from 1)		R142 D146 S177 R178 F179 T180 R191 D192 E217 K225 Y274 K277 R294 F343 P345 R346 F347 R366 W374 L386 H387 S404 P407 Y410 V418 Y478 V479 K483 K484 D485 K492 W495 S501 R503 R504 K509 R550 F551 P556 E560 H645 R653
Enzymatic activity
Enzyme Commision number ?
External links