Structure of PDB 8fss Chain A Binding Site BS01

Receptor Information

>8fss Chain A (length=571) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KESYAFAVLGEPRYAFNFNHFDYVNPAAPKGGQITLSALGTFDNFNRYAL
RGNPGARTEQLYDTLFTTSDDEPGSYYPLIAESARYADDYSWVEVAINPR
ARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTVKAIAPLTVRIEL
AKPGKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRVTSWKMGQ
NIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLR
MENDAKNWATRYTGNFYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVRE
AITLAFDFEWMNKALFYNAWSRTNSYFQNTEYAARNYPDAAELVLLAPMK
KDLPSEVFTQIYQPPVSKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNAT
TGQPLSFELLLPASSNSQWVLPFQHSLQRLGINMDIRKVDNSQITNRMRS
RDYDMMPRVWRAMPWPSSDLQIAWSSEYINSTYNAPGVQSPVIDSLINQI
IAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAWWDKFSQPAVR
PIYSLGIDTWWYDVNKAAKLP

Ligand information

>8fss Chain B (length=7) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

MRTGNAD

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8fss Trojan Horse Peptide Conjugates Remodel the Activity Spectrum of Clinical Antibiotics
Resolution	2.0 Å
Binding residue (original residue number in PDB)	R51 F125 V130 Q132 F133 Y137 D161 S164 R457 D477 I480 T490 Y491
Binding residue (residue number reindexed from 1)	R47 F121 V126 Q128 F129 Y133 D157 S160 R449 D469 I472 T482 Y483

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0015421	ABC-type oligopeptide transporter activity
GO:1904680	peptide transmembrane transporter activity

	Biological Process
GO:0006857	oligopeptide transport
GO:0015833	peptide transport
GO:0035672	oligopeptide transmembrane transport
GO:0042884	microcin transport
GO:0055085	transmembrane transport

	Cellular Component
GO:0016020	membrane
GO:0030288	outer membrane-bounded periplasmic space
GO:0043190	ATP-binding cassette (ABC) transporter complex
GO:0055052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function

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Cellular Component

External links

PDB	RCSB:8fss, PDBe:8fss, PDBj:8fss
PDBsum	8fss
PubMed
UniProt	P33913\|YEJA_ECOLI Uncharacterized protein YejA (Gene Name=yejA)

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