Structure of PDB 8fs5 Chain A Binding Site BS01

Receptor Information
>8fs5 Chain A (length=435) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EQWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHRILLLSGPSGC
SKSTVIKELSKILVPKYRQNHKVTEFRGDCIVNDLPQMESFSEFLKGARY
LVMSNLSLILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICITE
CEIPENDNNYRKFGIDYTFSAETIMNKEILMHPRLKRIKFNPINSTLLKK
HLKFICVQNMKMLKEKNKWNKRQEVIDYIAQETGDIRSAITTLQFWATSS
GSLPISTRESTISYFHAIGKVIHGSHSTNNDNEMINNLFENSNNLLSKED
FKLGILENYNTFNKGEFSISDASSIVDCLSECDNMNGLPESNEYGLREVR
KTFRNISKQGHNHGTVYFPREWKVRKLQNSFKVQAEDWLNVSLYKYNAVH
SFRNITLEFGYYAPLIRKCQSYKDVVDRIGGPIEA
Ligand information
Receptor-Ligand Complex Structure
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PDB8fs5 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Resolution2.76 Å
Binding residue
(original residue number in PDB)		K84 P161 Q162 M163 H194 Y235 K252 N266 N269 Y339 F340 V441 Y442 F443 W447 K451
Binding residue
(residue number reindexed from 1)		K21 P86 Q87 M88 H119 Y160 K177 N191 N194 Y264 F265 V366 Y367 F368 W372 K376
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003689 DNA clamp loader activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0031389 Rad17 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fs5, PDBe:8fs5, PDBj:8fs5
PDBsum8fs5
PubMed37205533
UniProtP32641|RAD24_YEAST Checkpoint protein RAD24 (Gene Name=RAD24)

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