Structure of PDB 8fn9 Chain A Binding Site BS01

Receptor Information
>8fn9 Chain A (length=219) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVFPHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIV
FQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVD
MRDGQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTE
DRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGH
EFSIPFVEMKMRPYNHRLM
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8fn9 Chain A Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8fn9 Protein-protein interactions between tenascin-R and RPTP zeta /phosphacan are critical to maintain the architecture of perineuronal nets.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		D1282 D1284 A1286 V1287 T1288
Binding residue
(residue number reindexed from 1)		D153 D155 A157 V158 T159
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8fn9, PDBe:8fn9, PDBj:8fn9
PDBsum8fn9
PubMed37356715
UniProtQ92752|TENR_HUMAN Tenascin-R (Gene Name=TNR)

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