Structure of PDB 8fja Chain A Binding Site BS01
Receptor Information
>8fja Chain A (length=274) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
Ligand information
>8fja Chain C (length=10) Species:
9606
(Homo sapiens) [
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GVYDGREHTV
Receptor-Ligand Complex Structure
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PDB
8fja
CryoEM structure of REGN6972 Fab in complex with HLA-A2 MAGEA4 (230-239)
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
Y7 K66 H70 T73 D77 Y99 Y116 T143 K146 W147 Y159 W167
Binding residue
(residue number reindexed from 1)
Y7 K66 H70 T73 D77 Y99 Y116 T143 K146 W147 Y159 W167
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8fja
,
PDBe:8fja
,
PDBj:8fja
PDBsum
8fja
PubMed
UniProt
Q861F7
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