Structure of PDB 8f16 Chain A Binding Site BS01

Receptor Information
>8f16 Chain A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GASPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCY
LKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA
YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERR
Ligand information
>8f16 Chain C (length=15) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PHEMCYWADAYCRYS
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8f16 Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display
Resolution1.56 Å
Binding residue
(original residue number in PDB)		F37 V38 Y49 N65 L71 K72 K95 F98 F99 Q102 E106 D134 A138 I141 K145
Binding residue
(residue number reindexed from 1)		F17 V18 Y29 N45 L51 K52 K75 F78 F79 Q82 E86 D114 A118 I121 K125
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:8f16, PDBe:8f16, PDBj:8f16
PDBsum8f16
PubMed
UniProtQ9UNE7|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)

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