Structure of PDB 8exx Chain A Binding Site BS01

Receptor Information
>8exx Chain A (length=1088) Species: 10306 (Human alphaherpesvirus 1 strain KOS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGG
DERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHA
YGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNK
EEVDRHLQDLCERMAAALRESPGASFRGISADHFEAEVVERTDVYYYETR
PALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNPGFVTFG
WYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADNLAIEGGMSDLPAYKL
MCFDIECKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEHVLLFSL
GSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGPEFVTG
YNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDIGQSHFQKRSK
IKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYY
ATGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIY
DGQQIRVFTCLLRLADQKGFILPDTQGRFRGAGGEAGRHVGYQGARVLDP
TSGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLE
IEVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLD
KQQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHA
RWAAFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTA
MGDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKG
VDLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLP
EGLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTV
YYKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLARKLLVSELAEDPA
YAIAHGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWH
PPDDVAARLRAAGFGAVGAGATAEETRRMLHRAFDTLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8exx Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		Y722 K811 N815 T887 D888 K939 Y941 K953 G954 V958 R959 K960 N961 E1036 R1039 Y1044 T1045 N1046 H1051 R1071
Binding residue
(residue number reindexed from 1)		Y618 K707 N711 T783 D784 K835 Y837 K849 G850 V854 R855 K856 N857 E932 R935 Y940 T941 N942 H947 R967
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