Structure of PDB 8ewo Chain A Binding Site BS01

Receptor Information
>8ewo Chain A (length=259) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMIQIDALPAFNDNYIWLLQDATSRRCAVVDPGDAKPVEAWLAAHPDWRL
SDILVTHHHHDHVGGVAALKELTGARVLGPANEKIPARDLALEDGERVEV
LGLVFEIFHVPGHTLGHIAYYHPAETPLLFCGDTLFAAGCGRLFEGTPAQ
MHHSLARLAALPANTRVYCTHEYTLSNLRFALAVEPDNAALRERFEEATR
LRERDRITLPSEISLELSTNPFLRVSENSVKKKADQRSGQQNRTPEEVFA
VLRAWKDQF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8ewo Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ewo Crystal structure of putative glyoxylase II from Pseudomonas aeruginosa
Resolution2.47 Å
Binding residue
(original residue number in PDB)		H56 H58 H112 D132
Binding residue
(residue number reindexed from 1)		H57 H59 H113 D133
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.2.6: hydroxyacylglutathione hydrolase.
Gene Ontology
Molecular Function
GO:0004416 hydroxyacylglutathione hydrolase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione

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Molecular Function
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Biological Process
External links
PDB RCSB:8ewo, PDBe:8ewo, PDBj:8ewo
PDBsum8ewo
PubMed
UniProtQ9I2T1|GLO2_PSEAE Hydroxyacylglutathione hydrolase (Gene Name=gloB)

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