Structure of PDB 8ev2 Chain A Binding Site BS01

Receptor Information
>8ev2 Chain A (length=233) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHI
RHMSNKGMEHLYSMKKNVVPLSDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ev2 Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors.
Resolution2.01 Å
Binding residue
(original residue number in PDB)		I358 K362 L372 V376 D538 L539 E542
Binding residue
(residue number reindexed from 1)		I54 K58 L68 V72 D223 L224 E227
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8ev2, PDBe:8ev2, PDBj:8ev2
PDBsum8ev2
PubMed36516582
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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