Structure of PDB 8esh Chain A Binding Site BS01
Receptor Information
>8esh Chain A (length=271) Species:
9606
(Homo sapiens) [
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SHSMRYFDTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAARMEPRAPWIE
QEGPEYWDRNTRIFKTNSQTDRESLGNLRGYYNQSEAGSHTLQSMYGCDV
GSDWRFLRGYNQNAYDGKDYIALKEDLRSWTAADMAAQITKHKWEAAHVA
EQDRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLRC
WALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQ
EQRYTCHVQHEGLPKPLTLRW
Ligand information
>8esh Chain C (length=9) Species:
10359
(Human betaherpesvirus 5) [
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ELNRKMIYM
Receptor-Ligand Complex Structure
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PDB
8esh
Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules.
Resolution
2.72 Å
Binding residue
(original residue number in PDB)
Y7 F36 R62 N63 I66 F67 N70 T73 E76 S77 Y84 Y99 N116 T143 W147 Y159 W167
Binding residue
(residue number reindexed from 1)
Y6 F35 R59 N60 I63 F64 N67 T70 E73 S74 Y81 Y96 N113 T140 W144 Y156 W164
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8esh
,
PDBe:8esh
,
PDBj:8esh
PDBsum
8esh
PubMed
36761745
UniProt
D2KZ37
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