Structure of PDB 8esa Chain A Binding Site BS01

Receptor Information
>8esa Chain A (length=273) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGCYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTELVETRPAGDGTFQKWAAVVVPSGQ
EQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
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PDB8esa Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM
Resolution3.4 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 D77 C84 Y99 Y123 T143 V152 Y159
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 D77 C84 Y99 Y123 T143 V152 Y159
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
Cellular Component
GO:0042612 MHC class I protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:8esa, PDBe:8esa, PDBj:8esa
PDBsum8esa
PubMed37100770
UniProtP61769|B2MG_HUMAN Beta-2-microglobulin (Gene Name=B2M);
Q53Z42

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