Structure of PDB 8esa Chain A Binding Site BS01
Receptor Information
>8esa Chain A (length=273) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGCYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTELVETRPAGDGTFQKWAAVVVPSGQ
EQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>8esa Chain C (length=12) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
GVYDGREHTVGC
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
8esa
Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 D77 C84 Y99 Y123 T143 V152 Y159
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 D77 C84 Y99 Y123 T143 V152 Y159
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
Cellular Component
GO:0042612
MHC class I protein complex
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:8esa
,
PDBe:8esa
,
PDBj:8esa
PDBsum
8esa
PubMed
37100770
UniProt
P61769
|B2MG_HUMAN Beta-2-microglobulin (Gene Name=B2M);
Q53Z42
[
Back to BioLiP
]