Structure of PDB 8ept Chain A Binding Site BS01

Receptor Information
>8ept Chain A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMEKLHQCYWKSGEPQSDDIEASRMKRAAAKHLIERYYHQLTEGCGNE
ACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLCDPHP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8ept Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8ept Differences in structure, dynamics and Zn-coordination between isoforms of human ubiquitin ligase UBE3A
ResolutionN/A
Binding residue
(original residue number in PDB)		C47 C52 C57 C86
Binding residue
(residue number reindexed from 1)		C47 C52 C57 C86
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
External links
PDB RCSB:8ept, PDBe:8ept, PDBj:8ept
PDBsum8ept
PubMed
UniProtQ05086|UBE3A_HUMAN Ubiquitin-protein ligase E3A (Gene Name=UBE3A)

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