Structure of PDB 8ei0 Chain A Binding Site BS01
Receptor Information
>8ei0 Chain A (length=132) Species:
9606
(Homo sapiens) [
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GASPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCY
LKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA
YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEE
Ligand information
>8ei0 Chain B (length=11) Species:
32630
(synthetic construct) [
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PCYEAWVLCEY
Receptor-Ligand Complex Structure
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PDB
8ei0
Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
Resolution
1.47 Å
Binding residue
(original residue number in PDB)
N34 F37 L68 K95 F98 F99 Q102 F131 D134
Binding residue
(residue number reindexed from 1)
N14 F17 L48 K75 F78 F79 Q82 F111 D114
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:8ei0
,
PDBe:8ei0
,
PDBj:8ei0
PDBsum
8ei0
PubMed
37914719
UniProt
Q9UNE7
|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)
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