Structure of PDB 8ehz Chain A Binding Site BS01
Receptor Information
>8ehz Chain A (length=129) Species:
9606
(Homo sapiens) [
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KSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYL
KMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAY
SLAKEQRLNFGDDIPSALRIAKKKRWNSI
Ligand information
>8ehz Chain C (length=10) Species:
32630
(synthetic construct) [
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CWEAWLLCET
Receptor-Ligand Complex Structure
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PDB
8ehz
Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
Resolution
2.06 Å
Binding residue
(original residue number in PDB)
K30 N34 N65 K72 K95 F98 F99 F131 D134
Binding residue
(residue number reindexed from 1)
K9 N13 N44 K51 K74 F77 F78 F110 D113
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:8ehz
,
PDBe:8ehz
,
PDBj:8ehz
PDBsum
8ehz
PubMed
37914719
UniProt
Q9UNE7
|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)
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