Structure of PDB 8eb2 Chain A Binding Site BS01
Receptor Information
>8eb2 Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>8eb2 Chain C (length=9) Species:
9606
(Homo sapiens) [
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SLLMWITQV
Receptor-Ligand Complex Structure
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PDB
8eb2
HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8eb2
,
PDBe:8eb2
,
PDBj:8eb2
PDBsum
8eb2
PubMed
36381658
UniProt
A0A140T9X5
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