Structure of PDB 8e7f Chain A Binding Site BS01

Receptor Information
>8e7f Chain A (length=614) Species: 615 (Serratia marcescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YQDPGRLGAPDSWKTAEFNRQWGLEAISAEFAYARGYTGKGITIGVIDNA
ILSHSEFSGKLTRLDNGSYNFSYDKQDNMSFGDHGTHVAGIAAAKRDGAG
MHGVAFDADIIGTKLNDYGNRNGREELIQSAARVINNSWGIAPDIRRDAK
GDIIWLPNGRPDYVAFVKSEVIAEMMRSKSSVEWGSEQPVPTGGHSAMST
LLRAARHGKLIVFSAGNYNNYNIPEAQKSLPYAFPDVLNNYLIVTNLSDE
NQLSVSSTSCGQTASYCVSAPGSDIYSTVGRLESNTGGAVNREAYNKGEL
SLNPGYGNKSGTSMAAPHVTGVAAVLMQRFPYMSADQISAVIKTTATDLG
VAGIDNLFGWGRVNLRDAINGPKMFITKEDIPQEYYVPGSYSEKQFVVNI
PGLGNIVEPGTPVERRCTSSECSFDSWSNDISGHGGLTKTGAGTLALLGN
NTYRGDTWVKQGVLAIDGSVASNVYIENSGTLSGEGTVGAFRAARSGSVA
PGNGIGTLHVLHDAIFDRGSQYNVEVADNGRSDKIAARRAFLNGGSVNVS
LERSQNLLSQNEAQSLLGNKYTILTTTDGVTGRFENANPSYPFVKVALDY
RGNDVGLGITRTDA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8e7f Chain A Residue 711 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8e7f Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D376 L377 V379 G381 D383
Binding residue
(residue number reindexed from 1)		D348 L349 V351 G353 D355
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.-
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8e7f, PDBe:8e7f, PDBj:8e7f
PDBsum8e7f
PubMed36859523
UniProtP09489|PRTS_SERMA Extracellular serine protease

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