Structure of PDB 8e3d Chain A Binding Site BS01

Receptor Information
>8e3d Chain A (length=111) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMR
KHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDH
LHRHLKKDGCN
Ligand information
Receptor-Ligand Complex Structure
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PDB8e3d Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
Resolution2.62 Å
Binding residue
(original residue number in PDB)
K389 Q392 G393 K396 R399 H400 T403 K408 F419 T420 R421 K424 K431 N455 R464 K473 R477 H480 R483
Binding residue
(residue number reindexed from 1)
K9 Q12 G13 K16 R19 H20 T23 K28 F39 T40 R41 K44 K51 N75 R84 K93 R97 H100 R103
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8e3d, PDBe:8e3d, PDBj:8e3d
PDBsum8e3d
PubMed36626981
UniProtO95365|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A (Gene Name=ZBTB7A)

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