Structure of PDB 8dwj Chain A Binding Site BS01

Receptor Information
>8dwj Chain A (length=339) Species: 2681598 (Escherichia phage T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIPWIDNEFAYRALAHLPKFTQVNNSSTFKLRFRCPVCGDSKTDQNKARG
WYYGDNNEGNIHCYNCNYHAPIGIYLKEFEPDLYREYIFEIRKEKGKSRP
IEKPKELPKQPEKKIIKSLPSCVRLDKLAEDHPIIKYVKARCIPKDKWKY
LWFTTEWPKLVNSIAPGTYKKEISEPRLVIPIYNANGKAESFQGRALKKD
APQKYITIEAYPEATKIYGVERVKDGDVYVLEGPIDSLFIENGIAITGGQ
LDLEVVPFKDRRVWVLDNEPRHPDTIKRMTKLVDAGERVMFWDKSPWKSK
DVNDMIRKEGATPEQIMEYMKNNIAQGLMAKMRLSKYAK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8dwj Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Resolution3.9 Å
Binding residue
(original residue number in PDB)
S43 D46 R51 Y66 N67 A203 Q205 K206 Y207
Binding residue
(residue number reindexed from 1)
S41 D44 R49 Y64 N65 A201 Q203 K204 Y205
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003896 DNA primase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0039693 viral DNA genome replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8dwj, PDBe:8dwj, PDBj:8dwj
PDBsum8dwj
PubMed37474605
UniProtP04520|PRIM_BPT4 DNA primase (Gene Name=61)

[Back to BioLiP]