Structure of PDB 8dvg Chain A Binding Site BS01
Receptor Information
>8dvg Chain A (length=277) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG
CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWELS
Ligand information
>8dvg Chain C (length=10) Species:
9606
(Homo sapiens) [
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VVVGAGGVGK
Receptor-Ligand Complex Structure
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PDB
8dvg
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Resolution
2.594 Å
Binding residue
(original residue number in PDB)
Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 E152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 E152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8dvg
,
PDBe:8dvg
,
PDBj:8dvg
PDBsum
8dvg
PubMed
37604828
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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